Automation Engineer - South West - Excellent Salary

A rapidly expanding Biotech client of mine is currently looking for a Lead Automation Engineer to join them on a permanent basis at their site in the Southwest of England.

Main Responsibilities:

  • Lead the automation effort within the T cell PD team acting as a central point of contact to provide strong links between PD, Manufacturing and Quality.
  • Act as an interface between the biology of the process and the engineering requirements of the automation strategy.
  • Provide bioengineering input to the development team, including tools to evaluate the COGS and capacity / cycle time benefits of various process and automation improvement options.
  • Project management working with a matrix team of individuals to progress automation strategies from Development into Manufacturing.
  • Generate and maintain an understanding of the cell therapy automation landscape.
  • In collaboration with the scientific technical leads from the T cell team, provide technical review of experimental designs, results, conclusions and the automation development plans for automation within the T cell PD team Development.
  • In conjunction with the T cell PD Group Leader, Head of Process Development and other parties from Quality and Manufacturing contribute to the strategic direction for T cell process automation to decrease COGS, increase manufacturing capacity and increase assurance of product quality.
  • Provide assistance during the tech transfer of fully developed process automation technology to the Manufacturing team for implementation and validation within GMP production.
  • Manage any outsourced development activities for T cell process automation with subcontractors, collaborating with the scientific and technical leads as appropriate.

Key Requirements:

  • BSc or higher qualification in relevant area; Biology, Engineering or, and ideally, Biochemical Engineering.
  • Significant post-academic, industrial experience working at the interface of biology and engineering is a must.
  • Experience with, or at least the awareness of, the particular challenges for autologous cell therapy process industrialisation is critical.
  • In depth experience in the automation, process development, optimization, and technology transfer of bioprocesses (involving some aspect of cell culture, if not cell therapy).
  • A deep understanding of technologies suitable for T cell isolation, activation, transduction and expansion are key and would need to be developed if not understood initially.
  • The ability to be able to critically compare and contrast automation options from a commercial, scientific, quality and regulatory standpoint is key to the success of the role.
  • Skill including leadership, communication, project planning, external stakeholder management and critically collaboration.
  • Significant experience of working in and leading matrix teams will be required
  • Knowledge of T cell biology, adoptive T cell therapy and gene therapy would be an advantage.
  • Knowledge of statistical experimental design (such as DoE) or multivariate data analysis would be a significant advantage.

Vacancy Summary:

Job type: Permanent

Location: Southwest England

Salary: Negotiable (DOE)

If you are interested in this role or know anyone who might be please get in touch with an up to date CV and I'll be in touch.

Job reference information
Advertiser Vivid Resourcing
Contact Name Jack Phillips
Telephone 02073241910 (Please reference Dice when calling)
Reference AE/SW/1003_1489165597